Description

Piperazinone, 3-(Hydroxymethyl)-, (3S)- (9Ci) is a high-purity, chiral piperazinone derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and chiral building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors requiring enantiomerically pure scaffolds.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of potential drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Asymmetric Synthesis Building Block: Utilized in the construction of complex, enantiomerically pure molecules due to its defined (3S) stereochemistry.
• Ligand and Catalyst Development: Serves as a precursor for novel chiral ligands and organocatalysts used in stereoselective transformations.
• Agrochemical Research: Intermediate in the synthesis of advanced, biologically active compounds for crop protection.
• Academic and R&D Laboratories: Used in methodological studies and the discovery of new chemical entities (NCEs).
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing of specialty chemicals.

Basic Information

Product Name	Piperazinone, 3-(Hydroxymethyl)-, (3S)- (9Ci)
CAS No.	405214-45-1
Molecular Formula	C5H10N2O2
Molecular Weight	130.15 g/mol
Synonyms	(3S)-3-(Hydroxymethyl)piperazin-2-one; (S)-3-(Hydroxymethyl)-2-piperazinone; (3S)-3-(Hydroxymethyl)-2-piperazinone; 3-(Hydroxymethyl)piperazin-2-one, (3S)-; 2-Piperazinone, 3-(hydroxymethyl)-, (3S)-; (S)-3-Hydroxymethyl-2-piperazinone; (S)-3-(Hydroxymethyl)piperazin-2-one; (3S)-3-Hydroxymethylpiperazin-2-one
EINECS	Contact for details

Quality Control

Our Piperazinone, 3-(Hydroxymethyl)-, (3S)- (9Ci) is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.