Description

2-Butenenitrile, 3-(5,7-Dihydro-5-Hydroxy-7-Oxo-6H-Pyrrolo[3,4-B]Pyrazin-6-Yl)- (9Ci) is a high-value, complex heterocyclic nitrile building block used in advanced organic synthesis. This compound is critical for research and development in medicinal chemistry, serving as a key precursor for novel pharmacologically active molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex heterocycles and targeted small molecule libraries.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other enzymatic pathways.
• Medicinal Chemistry Research: Used in the design and construction of complex molecular scaffolds for structure-activity relationship (SAR) studies and high-throughput screening.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and other high-value nitrogen-containing heterocycles.
• Bioconjugation & Probe Development: The reactive nitrile group can be utilized for the development of chemical probes and bioconjugation reagents in chemical biology.
• Academic & Institutional R&D: Serves as a reference standard and starting material for research in synthetic organic chemistry and heterocyclic chemistry at universities and research institutes.

Basic Information

Product Name	2-Butenenitrile, 3-(5,7-Dihydro-5-Hydroxy-7-Oxo-6H-Pyrrolo[3,4-B]Pyrazin-6-Yl)- (9Ci)
CAS No.	404340-71-2
Molecular Formula	C10H8N4O2
Molecular Weight	216.20 g/mol
Synonyms	3-(5,7-Dihydro-5-hydroxy-7-oxo-6H-pyrrolo[3,4-b]pyrazin-6-yl)-2-butenenitrile; 6-(1-Cyano-2-propenyl)-5-hydroxy-7H-pyrrolo[3,4-b]pyrazin-7-one; 3-(5-Hydroxy-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-6-yl)acrylonitrile; 404340-71-2; Pyrrolopyrazine acrylonitrile derivative; Heterocyclic nitrile intermediate
EINECS	Contact for details

Quality Control

Our 2-Butenenitrile, 3-(5,7-Dihydro-5-Hydroxy-7-Oxo-6H-Pyrrolo[3,4-B]Pyrazin-6-Yl)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with full analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); handle and store under an inert atmosphere such as nitrogen or argon for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.