Description

1-(4-Nitro-Benzenesulfonyl)-Piperazine Hydrochloride is a high-purity, functionalized piperazine derivative used as a critical building block in advanced organic synthesis. This compound is valued for its role as a versatile sulfonamide-protected piperazine intermediate, enabling the development of complex molecules with targeted properties. It is primarily required by research institutions and pharmaceutical companies engaged in the discovery and development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the piperazine and sulfonamide moieties for bioactivity.
• Chemical Biology & Proteomics: Serves as a scaffold or linker in the design of chemical probes and affinity tags for studying protein function and interactions.
• Material Science: Employed in the synthesis of specialty polymers and functional materials where the sulfonamide group can impart specific solubility or binding characteristics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	1-(4-Nitro-Benzenesulfonyl)-Piperazine Hydrochloride
CAS No.	403825-44-5
Molecular Formula	C10H14ClN3O4S
Molecular Weight	307.75 g/mol
Synonyms	1-(4-Nitrobenzenesulfonyl)piperazine hydrochloride; 4-Nitro-N-(piperazin-1-yl)benzenesulfonamide hydrochloride; Piperazine, 1-[(4-nitrophenyl)sulfonyl]-, hydrochloride; 1-(4-Nitro-phenylsulfonyl)-piperazine hydrochloride; 4-Nitrobenzenesulfonylpiperazine HCl; N-(4-Nitrobenzenesulfonyl)piperazine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(4-Nitro-Benzenesulfonyl)-Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.