Description

(2S)-2-Cyclohexyl-n-(2-Pyrazinylcarbonyl)Glycyl-3-Methyl-L-Valine is a specialized, non-natural amino acid derivative featuring a unique peptide-like structure. This compound is of significant value in advanced pharmaceutical research and development, particularly in the design of novel therapeutic peptides and protease inhibitors. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for applications in drug discovery and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex peptide-based drug candidates targeting various diseases.
• Protease Inhibitor Development: Used in the research and construction of molecules designed to inhibit specific enzymes like proteases, which are relevant in virology and oncology.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Peptidomimetic Synthesis: Employed to create peptidomimetics—molecules that mimic peptides but with enhanced metabolic stability and bioavailability.
• Bioconjugation: The reactive groups make it suitable for conjugation studies in chemical biology for creating targeted probes or drug conjugates.

Basic Information

Product Name	(2S)-2-Cyclohexyl-n-(2-Pyrazinylcarbonyl)Glycyl-3-Methyl-L-Valine
CAS No.	402958-96-7
Molecular Formula	C19H28N4O4
Molecular Weight	376.45 g/mol
Synonyms	(2S)-2-Cyclohexyl-N-(pyrazine-2-carbonyl)glycyl-3-methyl-L-valine; N-[(2S)-2-Cyclohexyl-2-[(pyrazine-2-carbonyl)amino]acetyl]-3-methyl-L-valine; (2S)-2-Cyclohexyl-2-[(pyrazin-2-ylformamido)acetamido]-3-methylbutanoic acid; Cyclohexyl-Pyrazinyl-Glycyl-3-Methyl-L-Valine; CPG-3-Methylvaline; 402958-96-7; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our (2S)-2-Cyclohexyl-n-(2-Pyrazinylcarbonyl)Glycyl-3-Methyl-L-Valine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 98.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.