Description

Acetic Acid-13C2,D4 is a stable isotope-labeled analog of acetic acid, where all carbon atoms are the carbon-13 isotope and all hydrogen atoms are deuterium. This compound is essential as an internal standard and tracer in quantitative mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy, providing unmatched accuracy for metabolic and pharmacokinetic studies. It is a critical reagent for researchers and quality control laboratories in the pharmaceutical, biotechnology, and analytical chemistry sectors who require precise quantification and pathway elucidation.

Application

• Quantitative Mass Spectrometry (MS): Serves as a high-purity internal standard for the accurate quantification of endogenous acetic acid and related metabolites in complex biological matrices like plasma, urine, and cell lysates.
• Metabolic Flux Analysis (MFA): Used as a stable isotope tracer to map and quantify metabolic pathways in living systems, providing insights into cellular metabolism in cancer research, microbiology, and systems biology.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Acts as a chemical shift reference and a tracer in NMR-based metabolic studies due to its distinct spectral signature, free from proton interference.
• Pharmaceutical Drug Development: Employed in Absorption, Distribution, Metabolism, and Excretion (ADME) studies and pharmacokinetic (PK) modeling to track drug metabolites and understand clearance pathways.
• Forensic and Doping Control Analysis: Provides a reliable benchmark in forensic toxicology and sports anti-doping programs for the definitive identification and measurement of substances.
• Environmental Science: Used in research tracing acetate metabolism in environmental samples and studying microbial processes in soil and water.

Basic Information

Product Name	Acetic Acid-13C2,D4
CAS No.	402835-82-9
Molecular Formula	13C2D4O2
Molecular Weight	64.07 g/mol
Synonyms	Acetic-d4 Acid-13C2; Deuterated Acetic Acid-13C2; [13C2]Acetic Acid-d4; Acetic-13C2-d4 Acid; Perdeuterated Acetic-13C2 Acid; (1,2-13C2)Acetic-d4 Acid; Ethanoic-13C2-d4 Acid; Isotopic Acetic Acid
EINECS	Contact for details

Quality Control

Every batch of Acetic Acid-13C2,D4 is manufactured and analyzed under strict quality systems. We guarantee high chemical, isotopic, and optical purity through advanced analytical techniques including NMR, MS, and HPLC. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing batch-specific results for identity, purity (assay), isotopic enrichment, and solvent residues. Our quality commitment ensures reliability for your most sensitive research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Clear, Colorless Liquid
Identification (IR)	Conforms to Standard
Assay (HPLC)	≥ 99.0% (Chemical Purity)
Isotopic Enrichment (MS)	≥ 99 atom % 13C ≥ 99 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.