Description

1-Piperazinepropanol,3,5-Dimethyl-,(3R,5S)-Rel-(9Ci) is a chiral piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel, high-value pharmaceutical actives. It is primarily required by research institutions and pharmaceutical companies engaged in the synthesis of complex molecules, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas where stereochemistry is crucial for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for CNS-targeting therapies.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes to explore novel chemical space.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and route development for active pharmaceutical ingredients (APIs).
• Chemical Biology: Used in the synthesis of molecular probes and tool compounds for studying biological pathways and target engagement.

Basic Information

Item	Detail
Product Name	1-Piperazinepropanol,3,5-Dimethyl-,(3R,5S)-Rel-(9Ci)
CAS No.	401812-00-8
Molecular Formula	C9H20N2O
Molecular Weight	172.27 g/mol
Synonyms	(3R,5S)-3,5-Dimethyl-1-piperazinepropanol; (3R,5S)-3,5-Dimethylpiperazin-1-yl-propan-1-ol; (3R,5S)-Rel-3,5-Dimethyl-1-(3-hydroxypropyl)piperazine; 1-[(3R,5S)-3,5-Dimethylpiperazin-1-yl]propan-1-ol; (R*,S*)-3,5-Dimethyl-1-(3-hydroxypropyl)piperazine; (rel)-(3R,5S)-3,5-Dimethyl-1-(3-hydroxypropyl)piperazine; 401812-00-8
EINECS	Contact for details

Quality Control

Our 1-Piperazinepropanol,3,5-Dimethyl-,(3R,5S)-Rel-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.