Description

1-Piperazinecarboxylic Acid, 4-(1,3-Dioxobutyl)-, 1,1-Dimethylethyl Ester is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for its reliable reactivity and structural versatility.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Peptidomimetics & Bioactive Molecule Synthesis: Employed to introduce the piperazine moiety into peptides and other bioactive compounds to modulate their pharmacokinetic properties.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Custom Chemical Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring protected amine functionality.

Basic Information

Product Name	1-Piperazinecarboxylic Acid, 4-(1,3-Dioxobutyl)-, 1,1-Dimethylethyl Ester
CAS No.	401566-77-6
Molecular Formula	C15H26N2O4
Molecular Weight	298.38 g/mol
Synonyms	tert-Butyl 4-(3-oxobutanoyl)piperazine-1-carboxylate; 4-Acetoacetyl-1-Boc-piperazine; 1-Boc-4-acetoacetylpiperazine; N-Boc-4-(3-oxobutanoyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(3-oxobutanoyl)piperazine; 4-(1,3-Dioxobutyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; Boc-4-acetoacetylpiperazine; 401566-77-6
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarboxylic Acid, 4-(1,3-Dioxobutyl)-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.