Description

Imino-Tris(Dimethylamino)Phosphorane CAS NO 49778-01-0 is a versatile organophosphorus compound, specifically a phosphazene base, known for its strong non-nucleophilic basicity. This property makes it an exceptionally valuable reagent for deprotonation reactions in sensitive organic syntheses where traditional bases may cause side reactions. It is a critical component for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, enabling the development of complex molecules with high precision.

Application

• Pharmaceutical Intermediate Synthesis: Used as a powerful, non-nucleophilic base for the generation of reactive carbanions and the deprotonation of weak acids in API (Active Pharmaceutical Ingredient) manufacturing.
• Polymer Chemistry Catalyst: Acts as an efficient catalyst or initiator in the ring-opening polymerization (ROP) of cyclic esters like lactides and lactones to produce biodegradable polymers.
• Agrochemical Production: Employed in the synthesis of complex pesticide and herbicide molecules where selective deprotonation is required under mild conditions.
• Ligand and Catalyst Preparation: Serves as a precursor or auxiliary base in the preparation of metal-organic complexes and catalysts used in fine chemical synthesis.
• Research & Development: A key reagent in academic and industrial R&D labs for exploring new synthetic methodologies and constructing complex molecular architectures.
• Electronic Chemicals: Utilized in the synthesis of specialty chemicals and precursors for electronic materials, including semiconductors and OLED components.

Basic Information

Product Name	Imino-Tris(Dimethylamino)Phosphorane
CAS No.	49778-01-0
Molecular Formula	C9H24N4P
Molecular Weight	219.29 g/mol
Synonyms	Phosphazene Base P1; Tris(dimethylamino)(imino)phosphorane; Hexamethylphosphorous triamide imide; P1-t-Bu Phosphazene Base; 1,1,1,3,3,3-Hexamethyl-2-(trimethylazanyl)phosphanediimine; Imino-tris(dimethylamino)phosphorane; Imino-tris(N,N-dimethylamino)phosphorane; P1-(tert-Butyl) Phosphazene Base
EINECS	256-459-0

Quality Control

Our Imino-Tris(Dimethylamino)Phosphorane is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and titration methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
NMR Purity (1H, 31P)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.