Description

3-Ethoxypropionyl Chloride is a versatile acid chloride derivative used as a key building block in organic synthesis. Its primary value lies in its reactivity as an acylating agent, enabling the efficient introduction of the 3-ethoxypropionyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediates: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing ester and amide linkages.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the ethoxypropionyl group is a critical functional component.
• Polymer Chemistry: Acts as a monomer or modifying agent in the production of specialty polymers and resins, imparting specific solubility or reactivity properties.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and other complex organic compounds requiring acyl chloride chemistry.
• Cross-coupling Reactions: Employed in palladium-catalyzed and other metal-mediated coupling reactions to create complex molecular architectures.
• Peptide Mimetics: Useful in medicinal chemistry for the synthesis of peptide analogs and bioisosteres.

Basic Information

Product Name	3-Ethoxypropionyl Chloride
CAS No.	49775-37-3
Molecular Formula	C5H9ClO2
Molecular Weight	136.58 g/mol
Synonyms	β-Ethoxypropionyl Chloride; 3-Ethoxypropanoyl Chloride; Ethoxypropanoic Acid Chloride; 3-Ethoxypropanoic Acid Chloride; NSC 404080; Ethyl 3-chloropropionate (related ester); Propionyl chloride, 3-ethoxy-
EINECS	Contact for details

Quality Control

Our 3-Ethoxypropionyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including assay by GC or titration and impurity profiling, to ensure it meets the high-purity standards required for synthetic applications. Certificates of Analysis (COA) documenting purity, identity, and specific impurity limits are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Impurities (GC)	≤ 1.0% (total)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.