Description

(1S,3As)-1,5,6,8,9,14Bβ-Hexahydro-2-Methoxy-1α,9α-Epoxy-4H-Cyclopenta[A][1,3]Dioxolo[4,5-H]Pyrrolo[2,1-B][3]Benzazepin-1β-Ol is a complex, high-purity alkaloid derivative with a unique polycyclic structure. This compound is valued for its role as a critical pharmaceutical intermediate and a sophisticated building block in advanced organic synthesis. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing novel therapeutic agents and conducting structure-activity relationship studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex alkaloid-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for designing and synthesizing new chemical entities for biological screening.
• Neurological Research: Serves as a reference standard or tool compound in studies targeting specific neurological pathways.
• Organic Synthesis Building Block: Employed in multi-step syntheses requiring its specific stereochemistry and functional groups.
• Analytical Reference Standard: Used in HPLC, LC-MS, or NMR for method development, validation, and quality control of related substances.

Basic Information

Item	Details
Product Name	(1S,3As)-1,5,6,8,9,14Bβ-Hexahydro-2-Methoxy-1α,9α-Epoxy-4H-Cyclopenta[A][1,3]Dioxolo[4,5-H]Pyrrolo[2,1-B][3]Benzazepin-1β-Ol
CAS No.	49686-61-5
Molecular Formula	C₂₀H₂₁NO₆
Molecular Weight	371.39 g/mol
Synonyms	Galantamine Impurity; Galantamine Related Compound A; 1,5,6,8,9,14Bβ-Hexahydro-2-methoxy-1α,9α-epoxy-4H-cyclopenta[A][1,3]dioxolo[4,5-H]pyrrolo[2,1-B][3]benzazepin-1β-ol; (1S,12bS)-1,2,3,4,6,7,12,12b-Octahydro-1-methoxy-indolo[2,3-a]quinolizine-3,8,9-triol 3,9-acetonide; Narwedine; Lycoramine Acetonide
EINECS	Contact for details

Quality Control

Our (1S,3As)-1,5,6,8,9,14Bβ-Hexahydro-2-Methoxy-1α,9α-Epoxy-4H-Cyclopenta[A][1,3]Dioxolo[4,5-H]Pyrrolo[2,1-B][3]Benzazepin-1β-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.