Description

Piperazine, 1-(3-Nitrophenyl)-4-(Phenylmethyl)- is a specialized piperazine derivative with a nitrophenyl and benzyl substituent, serving as a crucial synthetic intermediate in advanced organic chemistry. Its molecular architecture makes it a valuable building block for constructing complex pharmacologically active molecules and functional materials. This compound is primarily targeted at research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity, structurally defined intermediates for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the piperazine core's prevalence in bioactive molecules.
• Agrochemical Research: Used in developing new active ingredients for crop protection agents, leveraging its nitro and aromatic groups for structural diversity.
• Ligand and Catalyst Development: Serves as a starting material for creating complex chelating ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Potential monomer or functional additive in the development of advanced polymers with specific electronic or thermal properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	Piperazine, 1-(3-Nitrophenyl)-4-(Phenylmethyl)-
CAS No.	47228-63-7
Molecular Formula	C17H19N3O2
Molecular Weight	297.35 g/mol
Synonyms	1-Benzyl-4-(3-nitrophenyl)piperazine; 4-Benzyl-1-(3-nitrophenyl)piperazine; N-Benzyl-N'-(3-nitrophenyl)piperazine; 1-(3-Nitrophenyl)-4-(phenylmethyl)piperazine; 3-Nitro-1-(4-benzylpiperazin-1-yl)benzene; 1-(3-Nitrophenyl)-4-benzylpiperazine; 4-(3-Nitrophenyl)-1-benzylpiperazine
EINECS	Contact for details

Quality Control

Our Piperazine, 1-(3-Nitrophenyl)-4-(Phenylmethyl)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.