Description

1-Methyl-4-Tosylpiperazine is a versatile and high-purity chemical intermediate featuring a piperazine ring system functionalized with a tosyl protecting group. This compound is valued for its role in facilitating complex organic syntheses, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that require specific piperazine-based structures.
• Organic Synthesis Reagent: Serves as a protected piperazine derivative in multi-step synthetic routes for complex molecules in academic and industrial R&D.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed reactions and coordination chemistry.
• Chemical Research: Utilized as a standard or reference compound in analytical method development and metabolic studies.

Basic Information

Product Name	1-Methyl-4-Tosylpiperazine
CAS No.	46779-48-0
Molecular Formula	C12H18N2O2S
Molecular Weight	254.35 g/mol
Synonyms	1-Methyl-4-(4-methylphenyl)sulfonylpiperazine; 4-Methyl-1-(p-toluenesulfonyl)piperazine; N-Methyl-N'-tosylpiperazine; 1-Methyl-4-(p-toluenesulfonyl)piperazine; 1-Methyl-4-(toluene-4-sulfonyl)piperazine; 4-Tosyl-1-methylpiperazine; 1-Methyl-4-(4-methylbenzenesulfonyl)piperazine; Tosylmethylpiperazine
EINECS	Contact for details

Quality Control

Our 1-Methyl-4-Tosylpiperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.