Description

(2R,3R)-Piperazine-2,3-Dicarboxylic Acid CAS NO 46027-28-5 is a high-purity, chiral piperazine derivative, serving as a critical building block in advanced organic synthesis. Its defined stereochemistry makes it an invaluable intermediate for the development of novel pharmaceuticals and bioactive compounds. This product is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of complex drug molecules, particularly in central nervous system (CNS) and antiviral research.
• Ligand Synthesis: Used to create chiral ligands for asymmetric catalysis, enhancing the efficiency and selectivity of chemical reactions.
• Agrochemical Development: Serves as a precursor in the design of novel, stereospecific pesticides and herbicides.
• Peptidomimetics Research: Integral component in the design of peptide analogs and conformationally restricted scaffolds for medicinal chemistry.
• Chemical Biology Probes: Employed in the development of molecular probes to study enzyme mechanisms and biological pathways.
• Fine Chemical Synthesis: A versatile starting material for the production of specialty chemicals requiring a chiral piperazine core.

Basic Information

Product Name	(2R,3R)-Piperazine-2,3-Dicarboxylic Acid
CAS No.	46027-28-5
Molecular Formula	C6H10N2O4
Molecular Weight	174.15 g/mol
Synonyms	(2R,3R)-2,3-Piperazinedicarboxylic Acid; (2R,3R)-Piperazine-2,3-dicarboxylic Acid; (2R,3R)-2,3-Dicarboxypiperazine; (2R,3R)-PDCA; (2R,3R)-Piperazine-2,3-dicarboxylate; (2R,3R)-2,3-Piperazinedicarboxylate; (2R,3R)-2,3-Pyrazinedicarboxylic Acid (common misnomer); L-(+)-Tartaric acid derived piperazine dicarboxylic acid
EINECS	Contact for details

Quality Control

Our (2R,3R)-Piperazine-2,3-Dicarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.