Description

2,5-Dibromopiperidine is a versatile brominated heterocyclic building block of significant importance in advanced organic synthesis. Its value lies in its dual reactive bromine sites, which enable selective functionalization and the construction of complex nitrogen-containing molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it serves as a key intermediate for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of piperidine-based active pharmaceutical ingredients (APIs), including potential candidates for neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the piperidine scaffold for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating complex nitrogen-donor ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for introducing bromine handles into polymers for further derivatization.
• Custom Synthesis and R&D: A valuable reagent for medicinal chemistry and process research & development (R&D) in contract research organizations (CROs) and fine chemical companies.

Basic Information

Product Name	2,5-Dibromopiperidine
CAS No.	46026-75-9
Molecular Formula	C5H9Br2N
Molecular Weight	242.94 g/mol
Synonyms	2,5-Dibromopiperidine; Piperidine, 2,5-dibromo-; 2,5-Dibromo-piperidine; 2,5-Dibromopiperidin; NSC 169102; 2,5-Dibromohexahydropyridine; 2,5-Dibromo-1-azacyclohexane
EINECS	Contact for details

Quality Control

Our 2,5-Dibromopiperidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. For customers with specific regulatory needs, we can support documentation for GMP or ISO-guided applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.