Description

Piperazine-1-Carboxamidine is a high-purity chemical building block and intermediate of significant importance in advanced organic synthesis. Its core value lies in its functional guanidine group attached to a piperazine scaffold, making it a versatile precursor for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of various drug candidates, particularly those targeting neurological and cardiovascular diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Bioconjugation & Linker Chemistry: The reactive amidine group facilitates its use in creating molecular linkers and probes for biochemical and diagnostic applications.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology Tool: Employed in the design of enzyme inhibitors and receptor ligands for proteomics and drug discovery research.

Basic Information

Product Name	Piperazine-1-Carboxamidine
CAS No.	45695-84-9
Molecular Formula	C6H13N5
Molecular Weight	155.20 g/mol
Synonyms	1-Piperazinecarboximidamide; Piperazine-1-carboxamidine; 1-(Piperazin-1-yl)methanimidamide; 1-Piperazinylformamidine; 1-Piperazinecarboxamidine; 1-Piperazinylmethanimidamide; Guanidine, N-(1-piperazinyl)-; N-(Piperazin-1-yl)formamidine
EINECS	Contact for details

Quality Control

Our Piperazine-1-Carboxamidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.