Description

2-Chloro-3-(Chloromethyl)Pyrazine is a versatile and highly functionalized pyrazine derivative, serving as a critical building block in advanced organic synthesis. Its dual reactive sites—the chloromethyl group and the chlorine atom on the aromatic ring—make it an invaluable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the pyrazine core's bioactivity.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create specialized ligands for catalytic processes.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of functional polymers and advanced materials.
• Chemical Biology Probes: Useful for synthesizing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis and R&D: Serves as a starting material for contract research organizations and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	2-Chloro-3-(Chloromethyl)Pyrazine
CAS No.	45660-95-5
Molecular Formula	C5H4Cl2N2
Molecular Weight	163.00 g/mol
Synonyms	2-Chloro-3-(chloromethyl)pyrazine; 3-(Chloromethyl)-2-chloropyrazine; 2-Chloro-3-chloromethylpyrazine; Pyrazine, 2-chloro-3-(chloromethyl)-; (Chloromethyl)-2-chloropyrazine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3-(Chloromethyl)Pyrazine is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.