Description

1,2-o-Dioctadecyl-Rac-Glycero-3-Phosphocholine is a high-purity synthetic phospholipid, specifically a saturated phosphatidylcholine analogue with two identical C18 (stearyl) chains. This compound is a critical building block for creating stable, well-defined lipid bilayers and vesicles, making it essential for advanced research and formulation development. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and nanotechnology sectors who require precise control over membrane properties and model systems.

Application

• Liposome & Nanoparticle Formulation: A key component for constructing stable, unilamellar vesicles (LUVs, MLVs) used in drug delivery systems for encapsulating therapeutic agents.
• Membrane Biophysics Research: Serves as a primary lipid for creating model membranes and lipid bilayers to study membrane fluidity, protein-lipid interactions, and phase behavior.
• Biomimetic Coatings & Sensors: Used to create supported lipid bilayers (SLBs) on solid substrates for biosensor development, surface functionalization, and cell membrane mimicry.
• Cell Culture & Transfection Reagents: A component in specialized lipid mixtures for creating synthetic cell culture substrates and as a helper lipid in some non-viral transfection protocols.
• Reference Standard & Analytical Chemistry: Employed as a high-purity standard in chromatographic analysis (HPLC, LC-MS) for lipidomics and quality control of lipid-based products.
• Stabilizer for Emulsions & Dispersions: Acts as a biocompatible surfactant and stabilizer in complex emulsion systems for cosmetic and pharmaceutical applications.

Basic Information

Product Name	1,2-o-Dioctadecyl-Rac-Glycero-3-Phosphocholine
CAS No.	45322-29-0
Molecular Formula	C46H94NO6P
Molecular Weight	788.21 g/mol
Synonyms	DSPC (common abbreviation); 1,2-Distearyl-sn-glycero-3-phosphocholine (rac); Distearoylphosphatidylcholine (saturated analogue); 1,2-Di-O-octadecyl-rac-glycero-3-phosphocholine; 3-sn-Phosphatidylcholine, 1,2-di-O-octadecyl-rac-glycerol; DODPC; 1,2-Di-O-stearyl-rac-glycero-3-phosphorylcholine; L-α-Phosphatidylcholine, 1,2-di-O-octadecyl-rac-glycerol
EINECS	Contact for details

Quality Control

Our 1,2-o-Dioctadecyl-Rac-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and formulation. Certificates of Analysis (COA) detailing purity, chromatographic profiles, and other critical parameters are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
Solubility	Soluble in chloroform, ethanol; insoluble in water
Loss on Drying	≤ 1.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.