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1-Octanoyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine CAS NO 45287-18-1


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CAS No.:45287-18-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Octanoyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine is a synthetic, high-purity lysophospholipid, specifically a lysophosphatidylcholine (LPC) with an octanoyl (C8:0) chain. This compound is a critical biochemical tool and a key intermediate in lipid research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical, and cosmetic industries for applications ranging from membrane studies to drug delivery systems.

Application

  • Biochemical Research: Essential for studying lipid metabolism, cell membrane dynamics, and phospholipase A2 (PLA2) enzyme activity.
  • Pharmaceutical Development: Used as a key intermediate in the synthesis of more complex phospholipids and as a component in lipid-based drug delivery systems, including liposomes and lipid nanoparticles (LNPs).
  • Cell Culture & Signaling Studies: Acts as a bioactive lipid mediator in cell signaling pathways, particularly those involving G-protein-coupled receptors (GPCRs).
  • Cosmetic Formulations: Employed as a high-performance emulsifier and skin-conditioning agent in advanced skincare products.
  • Analytical Standards: Serves as a certified reference material (CRM) for quantitative analysis in lipidomics and quality control laboratories.
  • Diagnostic Reagents: Used in the formulation of reagents for clinical diagnostics, particularly in assays measuring phospholipid-related enzymes.

Basic Information

Product Name 1-Octanoyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine
CAS No. 45287-18-1
Molecular Formula C16H34NO7P
Molecular Weight 383.42 g/mol
Synonyms Lyso-PC (8:0); 1-Octanoyl-2-hydroxy-sn-glycero-3-phosphocholine; LPC 8:0; sn-Glycero-3-phosphocholine, 1-octanoyl-2-hydroxy-; Lysophosphatidylcholine (8:0/0:0); Octanoyl lysophosphatidylcholine; 1-Capryloyl-2-hydroxy-sn-glycero-3-phosphocholine; 1-Octanoyl-sn-glycero-3-phosphocholine
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Quality Control

Our 1-Octanoyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research and cGMP-grade standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white powder or waxy solid
Identification (HPLC/MS) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 3.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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