Description

(1S,5R)-(-)-2-Oxabicyclo[3.3.0]Oct-6-En-3-One is a high-purity, chiral bicyclic lactone that serves as a critical synthetic building block in advanced organic chemistry. Its unique fused ring structure and defined stereochemistry make it an invaluable precursor for synthesizing complex, biologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for creating novel drug candidates and chiral intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of prostaglandins, nucleoside analogs, and other complex therapeutic agents.
• Asymmetric Synthesis: Used as a starting material or chiral auxiliary in stereoselective reactions to construct molecules with high enantiomeric purity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.
• Agrochemical Synthesis: Potential intermediate for creating chiral active ingredients in advanced crop protection products.

Basic Information

Product Name	(1S,5R)-(-)-2-Oxabicyclo[3.3.0]Oct-6-En-3-One
CAS No.	43119-28-4
Molecular Formula	C7H8O2
Molecular Weight	124.14 g/mol
Synonyms	(-)-2-Oxabicyclo[3.3.0]oct-6-en-3-one; (1S,5R)-2-Oxabicyclo[3.3.0]oct-6-en-3-one; (3aR,6aS)-3a,4,6,6a-Tetrahydro-2H-cyclopenta[b]furan-2-one; (-)-Corey Lactone Diol Precursor; Corey Lactone Intermediate; Bicyclic γ-Lactone
EINECS	Contact for details

Quality Control

Every batch of (1S,5R)-(-)-2-Oxabicyclo[3.3.0]Oct-6-En-3-One is manufactured and tested under strict quality management systems to ensure high chemical and chiral purity. Our products undergo rigorous analytical testing, including chiral HPLC, to confirm identity, potency, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.