Description

(2S)-2,3-Dihydro-5,5',7,7'-Tetrahydroxy-2,2'-Bis(4-Hydroxyphenyl)-8,8'-Bi[4H-1-Benzopyran-4-One] is a high-purity, complex biflavonoid compound valued for its specific stereochemistry and potent biological activity. This compound is critical for advanced research and development in life sciences, where precise molecular structure directly influences efficacy and study outcomes. It is primarily sought by pharmaceutical R&D teams, nutraceutical formulators, and academic researchers focusing on natural product chemistry and bioactive compound discovery.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block or reference standard in the synthesis and development of novel therapeutic agents.
• Biochemical Research: Used as a high-purity standard or probe in studies investigating flavonoid metabolism, enzyme inhibition, and antioxidant mechanisms.
• Nutraceutical Development: Incorporated into advanced formulations for dietary supplements targeting oxidative stress, leveraging its bioactive flavonoid structure.
• Cosmeceutical Actives: Evaluated for use in premium skincare products for its potential antioxidant and skin-protective properties.
• Analytical Reference Standard: Provides a certified reference material for quality control and method validation in analytical laboratories (HPLC, LC-MS).
• Natural Product Isolation & Synthesis: Acts as a target molecule for synthetic organic chemists and a marker compound for the isolation and characterization of natural extracts.

Basic Information

Product Name	(2S)-2,3-Dihydro-5,5',7,7'-Tetrahydroxy-2,2'-Bis(4-Hydroxyphenyl)-8,8'-Bi[4H-1-Benzopyran-4-One]
CAS No.	43043-20-5
Molecular Formula	C₃₀H₂₂O₁₂
Molecular Weight	574.49 g/mol
Synonyms	GB-1a (Ginkgo Biloba biflavone); (2S)-Amentoflavone; (2S)-Bilobetin; (2S)-5,5',7,7'-Tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-3,8'-biflavone; (2S)-Dihydroamentoflavone; (2S)-Tetrahydroamentoflavone; (2S)-GB1a; (2S)-Isoginkgetin (related isomer).
EINECS	Contact for details

Quality Control

Our (2S)-2,3-Dihydro-5,5',7,7'-Tetrahydroxy-2,2'-Bis(4-Hydroxyphenyl)-8,8'-Bi[4H-1-Benzopyran-4-One] is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% (2S-isomer)
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.