Description

Methyl (R)-Piperidine-2-Carboxylate is a high-purity chiral building block of significant importance in asymmetric synthesis. This compound matters as a key intermediate for constructing complex molecules with defined stereochemistry, enabling the development of more potent and selective active pharmaceutical ingredients. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel compounds and active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of various APIs, particularly in the development of neurological and cardiovascular drugs.
• Asymmetric Synthesis: Used as a versatile building block in stereoselective reactions to introduce the (R)-pipecolic acid moiety.
• Agrochemical Research: Serves as a precursor in the development of novel, chiral pesticides and herbicides with enhanced activity.
• Catalyst and Ligand Preparation: Employed in the synthesis of chiral catalysts and ligands for enantioselective transformations.
• Peptidomimetics and Bioactive Molecule Design: Integral for creating conformationally constrained peptide analogs and other bioactive scaffolds.
• Academic and R&D Laboratories: A valuable reagent for methodological development and exploratory chemistry in academic and industrial research settings.

Basic Information

Product Name	Methyl (R)-Piperidine-2-Carboxylate
CAS No.	43041-11-8
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(R)-Methyl pipecolate; (R)-Methyl pipecolinate; Methyl (R)-(-)-Pipecolinate; (R)-Pipecolinic Acid Methyl Ester; (R)-2-Piperidinecarboxylic Acid Methyl Ester; (R)-Methyl 2-piperidinecarboxylate; (R)-Pipecolic Acid Methyl Ester; (R)-Homoproline Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl (R)-Piperidine-2-Carboxylate is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes rigorous analytical testing, including chiral HPLC, to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) with detailed chromatographic data are available upon request for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.