Description

1-(2-Chloroacetyl)-4-Methylpiperazine Hcl is a high-purity, versatile pharmaceutical intermediate and organic building block. Its value lies in its role as a key synthon for constructing complex molecules, particularly in medicinal chemistry and active pharmaceutical ingredient (API) development. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality raw materials for synthesis and process development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those with piperazine-based structures.
• Medicinal Chemistry Research: Used in research and development for creating novel chemical entities and exploring structure-activity relationships (SAR).
• Agrochemical Synthesis: Serves as a precursor in the manufacturing of certain herbicides, fungicides, and other crop protection agents.
• Fine Chemical Production: Employed in the multi-step synthesis of complex specialty chemicals, dyes, and functional materials.
• Chemical Biology Probes: Can be utilized to develop molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and contract research organizations (CROs/CMOs).

Basic Information

Product Name	1-(2-Chloroacetyl)-4-Methylpiperazine Hcl
CAS No.	42951-91-7
Molecular Formula	C7H14Cl2N2O
Molecular Weight	213.11 g/mol
Synonyms	1-(2-Chloroacetyl)-4-methylpiperazine hydrochloride; 4-Methyl-1-(2-chloroacetyl)piperazine hydrochloride; 2-Chloro-1-(4-methylpiperazin-1-yl)ethanone hydrochloride; N-(2-Chloroacetyl)-N'-methylpiperazine hydrochloride; 1-(Chloroacetyl)-4-methylpiperazine HCl; 42951-91-7; 4-Methylpiperazine-1-(2-chloroacetyl) hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2-Chloroacetyl)-4-Methylpiperazine Hcl is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.