Description

(R)-3-Quinuclidinol Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. This compound is valued for its rigid, bicyclic structure which serves as a key scaffold in medicinal chemistry for developing active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel therapeutics, particularly in the areas of central nervous system (CNS) agents and anticholinergic drugs.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the synthesis of muscarinic receptor antagonists and other bioactive molecules.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the research and production of new drug candidates.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical reactions.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new pharmacophores and structure-activity relationships (SAR).
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(R)-3-Quinuclidinol Hydrochloride
CAS No.	42437-96-7
Molecular Formula	C7H14ClNO
Molecular Weight	163.65 g/mol
Synonyms	(R)-3-Quinuclidinol HCl; (3R)-Quinuclidin-3-ol Hydrochloride; (R)-(+)-3-Quinuclidinol Hydrochloride; (+)-3-Quinuclidinol Hydrochloride; (R)-1-Azabicyclo[2.2.2]octan-3-ol Hydrochloride; (R)-3-Hydroxyquinuclidine Hydrochloride; (R)-Quinuclidinol Hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-3-Quinuclidinol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.