Description

2-Pyrrolidinecarbonyl Chloride, 1-Methyl-5-Oxo- (9Ci) is a versatile and highly reactive organic intermediate, primarily valued for its role as a key building block in complex organic synthesis. Its significance lies in its ability to introduce the 1-methyl-5-oxopyrrolidine-2-carbonyl moiety, a structural motif of considerable interest in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of various drug candidates, including potential protease inhibitors, nootropics, and other bioactive molecules containing the pyrrolidinone scaffold.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its reactive acid chloride group facilitates the creation of novel amide or ester derivatives.
• Organic Synthesis Reagent: Serves as a versatile reagent for peptide coupling and acylation reactions in academic and industrial R&D laboratories for constructing complex molecular architectures.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials that require the incorporation of a substituted pyrrolidinone ring system.

Basic Information

Product Name	2-Pyrrolidinecarbonyl Chloride, 1-Methyl-5-Oxo- (9Ci)
CAS No.	42435-90-5
Molecular Formula	C6H8ClNO2
Molecular Weight	161.59 g/mol
Synonyms	1-Methyl-5-oxopyrrolidine-2-carbonyl chloride; 1-Methyl-2-pyrrolidinone-5-carbonyl chloride; 5-Oxo-1-methyl-2-pyrrolidinecarbonyl chloride; N-Methyl-2-oxopyrrolidine-5-carbonyl chloride; 2-Carbamoyl-1-methylpyrrolidin-5-one chloride; (1-Methyl-5-oxopyrrolidin-2-yl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinecarbonyl Chloride, 1-Methyl-5-Oxo- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.