Description

(1R,8Ar)-1,2,3,7,8,8A-Hexahydro-1,6-Dimethyl-4-Isopropylnaphthalene is a high-purity, stereochemically defined decalin derivative with significant utility as a key chiral intermediate and building block in advanced organic synthesis. Its rigid, fused-ring structure and defined stereochemistry make it valuable for constructing complex molecular architectures where precise spatial orientation is critical. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fragrance industries, particularly for developing active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a chiral scaffold for the synthesis of novel drug candidates, particularly in steroid-like molecules and complex natural product analogs.
• Agrochemical Synthesis: Used as a building block for creating advanced pesticides and herbicides with specific stereochemical activity.
• Fragrance and Flavor Chemistry: Acts as a precursor for synthetic musks and other complex odorants due to its stable, polycyclic framework.
• Material Science Research: Employed in the development of liquid crystals and specialty polymers where a rigid, hydrophobic core is required.
• Catalyst and Ligand Development: Utilized as a backbone for synthesizing chiral ligands used in asymmetric catalysis.
• Organic Synthesis Standard: Functions as a reference standard and a model compound in methodological development and analytical chemistry.

Basic Information

Product Name	(1R,8Ar)-1,2,3,7,8,8A-Hexahydro-1,6-Dimethyl-4-Isopropylnaphthalene
CAS No.	41929-05-9
Molecular Formula	C₁₅H₂₄
Molecular Weight	204.35 g/mol
Synonyms	(1R,8aR)-1,2,3,7,8,8a-Hexahydro-1,6-dimethyl-4-(1-methylethyl)naphthalene; (1R,8aR)-4-Isopropyl-1,6-dimethyl-1,2,3,7,8,8a-hexahydronaphthalene; (+)-Calamenene; (R,R)-Calamenene; 1,2,3,7,8,8a-Hexahydro-1,6-dimethyl-4-(1-methylethyl)-(1R,8aR)-Naphthalene; Decahydro-1,6-dimethyl-4-(1-methylethyl)-, (1R,8aR)-Naphthalene
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chiral intermediates. Every batch of (1R,8Ar)-1,2,3,7,8,8A-Hexahydro-1,6-Dimethyl-4-Isopropylnaphthalene is analyzed using advanced chromatographic and spectroscopic techniques to ensure high chemical and stereochemical purity. Our quality system is designed to meet the rigorous demands of cGMP and ISO standards for advanced synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage under an inert atmosphere (e.g., nitrogen or argon), please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to reference spectrum
Identification (GC/MS)	Conforms to reference standard
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.