Description

Lonaprofen CAS NO 41791-49-5 is a non-steroidal anti-inflammatory drug (NSAID) belonging to the arylpropionic acid class. It is valued for its potent anti-inflammatory, analgesic, and antipyretic properties, making it a key intermediate in pharmaceutical synthesis. This compound is primarily required by manufacturers in the pharmaceutical industry for the research, development, and production of advanced therapeutic formulations.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active pharmaceutical ingredient in anti-inflammatory and analgesic medications.
• Research & Development: Critical intermediate in the synthesis and development of novel NSAID drug candidates and prodrugs.
• Veterinary Medicine: Used in formulations for managing pain and inflammation in animals.
• Analytical Reference Standard: Serves as a high-purity standard for quality control and analytical method development in laboratories.
• Topical Formulations: Incorporated into gels, creams, and patches for localized pain relief.
• Combination Drug Therapy: Used in fixed-dose combination products to enhance therapeutic efficacy.

Basic Information

Product Name	Lonaprofen
CAS No.	41791-49-5
Molecular Formula	C15H12O3
Molecular Weight	240.26 g/mol
Synonyms	2-(4-Isobutylphenyl)propionic acid; (±)-2-(4-Isobutylphenyl)propanoic acid; p-Isobutylhydratropic acid; (±)-Ibuprofen; DL-Ibuprofen; 4-Isobutyl-α-methylphenylacetic acid; (±)-p-Isobutylhydratropic acid; RS-Ibuprofen
EINECS	255-520-1

Quality Control

Our Lonaprofen is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications, including identification, assay, and impurity profile analysis. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing all test results against established specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.