Description

1-Hydroxyvitamin D3 Diacetate is a key synthetic intermediate in the production of active vitamin D metabolites and analogs. This compound is essential for pharmaceutical research and development, particularly in creating treatments for bone disorders and conditions related to calcium metabolism. It is primarily utilized by fine chemical manufacturers and R&D laboratories in the pharmaceutical and nutraceutical industries for the synthesis of advanced therapeutic agents.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of active vitamin D analogs like calcitriol and its derivatives.
• Research & Development: Used in biochemical research to study vitamin D metabolism, receptor binding, and signaling pathways.
• Fine Chemical Synthesis: Serves as a building block for creating novel compounds with potential therapeutic applications in osteoporosis and psoriasis.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for HPLC and LC-MS methods.
• Nutraceutical Development: Investigated for use in advanced nutritional supplements targeting bone health.

Basic Information

Product Name	1-Hydroxyvitamin D3 Diacetate
CAS No.	41461-12-5
Molecular Formula	C₂₉H₄₄O₅
Molecular Weight	460.66 g/mol
Synonyms	1α-Hydroxyvitamin D3 Diacetate; 1α-Hydroxycholecalciferol Diacetate; (5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1α,3β-diol Diacetate; 1α-OH-D3 Diacetate; 1α-Hydroxy Vitamin D3 Diacetate; 1α-Hydroxyergocalciferol Diacetate; 1α-Hydroxycolecalciferol Diacetate; 1α,25-Dihydroxyvitamin D3 Diacetate Precursor
EINECS	Contact for details

Quality Control

Our 1-Hydroxyvitamin D3 Diacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical intermediates. Certificates of Analysis (COA) are available upon request, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solvent Residues (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.