Description

Piperazin-1-Yl-Piperidin-1-Yl-Methanone is a high-purity chemical building block and pharmaceutical intermediate of significant commercial importance. Its core value lies in its versatile piperazine-piperidine amide scaffold, which is a privileged structure in medicinal chemistry for designing bioactive molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within the central nervous system (CNS) and oncology fields.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold or building block in structure-activity relationship (SAR) studies and combinatorial chemistry libraries.
• CNS Drug Discovery: Employed in the synthesis of potential therapeutics for neurological disorders, leveraging the pharmacophore properties of the piperazine and piperidine moieties.
• Oncology Research: Serves as an intermediate in the synthesis of investigational compounds for cancer treatment.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological processes and target validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	Piperazin-1-Yl-Piperidin-1-Yl-Methanone
CAS No.	41340-88-9
Molecular Formula	C10H19N3O
Molecular Weight	197.28 g/mol
Synonyms	1-(1-Piperazinyl)-1-piperidinecarboxamide; 1-Piperazinecarboxamide, N-1-piperidinyl-; N-(Piperidin-1-yl)piperazine-1-carboxamide; 1-Piperidinyl 1-Piperazinecarboxylate; Piperazin-1-yl(piperidin-1-yl)methanone; Piperazine-1-carboxylic acid piperidide; 41340-88-9; N-Piperidinylpiperazine-1-carboxamide
EINECS	Contact for details

Quality Control

Our Piperazin-1-Yl-Piperidin-1-Yl-Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.