Description

2-Chloro-3-Phenylpyrazine is a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its dual functionality, where the chlorine atom offers a reactive site for cross-coupling reactions, and the phenylpyrazine scaffold serves as a key pharmacophore. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components, due to its conjugated system.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	2-Chloro-3-Phenylpyrazine
CAS No.	41270-65-9
Molecular Formula	C10H7ClN2
Molecular Weight	190.63 g/mol
Synonyms	3-Phenyl-2-chloropyrazine; 2-Chloro-3-phenylpyrazine; Pyrazine, 2-chloro-3-phenyl-; 2-Chlor-3-phenylpyrazin (German); 2-クロロ-3-フェニルピラジン (Japanese); 2-氯-3-苯基吡嗪 (Chinese); 41270-65-9 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Phenylpyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.