Description

1-(2-Chlorophenyl)Piperazine Hydrochloride is a high-purity, versatile organic building block and pharmaceutical intermediate of significant commercial importance. Its value lies in its role as a key synthon for constructing complex molecules, particularly in medicinal chemistry and advanced material science. This compound is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers engaged in the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and specialized organic compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various therapeutic agents, including central nervous system (CNS) drugs and receptor-targeted compounds.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in drug discovery programs.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and pesticides.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development, validation, and quality control in regulatory and research settings.
• Organic Synthesis Building Block: Facilitates the construction of complex piperazine-containing heterocycles and other specialty organic molecules.
• Biochemical Research: Utilized in studies involving enzyme inhibition, receptor binding assays, and other pharmacological investigations.

Basic Information

Product Name	1-(2-Chlorophenyl)Piperazine Hydrochloride
CAS No.	41202-32-8
Molecular Formula	C10H14Cl2N2
Molecular Weight	233.14 g/mol
Synonyms	1-(2-Chlorophenyl)piperazine hydrochloride; 2-Chlorophenylpiperazine hydrochloride; o-Chlorophenylpiperazine hydrochloride; 1-(2-Chloro-phenyl)-piperazine hydrochloride; N-(2-Chlorophenyl)piperazine hydrochloride; 2-CPP hydrochloride; CPZ HCl; CAS 41202-32-8
EINECS	Contact for details

Quality Control

Our 1-(2-Chlorophenyl)Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.