Description

4-Hexynoic Acid (CAS NO 41143-12-8) is a versatile alkyne-containing carboxylic acid that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a terminal alkyne and a carboxylic acid functional group, makes it an invaluable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for applications ranging from medicinal chemistry to polymer modification.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those requiring alkyne handles for click chemistry.
• Agrochemical Synthesis: Used in the production of specialized herbicides, fungicides, and plant growth regulators that benefit from its reactive alkyne moiety.
• Material Science & Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers, coatings, and adhesives with tailored properties.
• Organic Synthesis & Research: A fundamental reagent for constructing carbon-carbon bonds via Sonogashira, Glaser, and other coupling reactions in academic and industrial laboratories.
• Liquid Crystal & Electronic Material Precursor: Employed in the development of advanced organic electronic materials and liquid crystal displays (LCDs).
• Bioconjugation & Probe Development: Utilized in bioconjugation chemistry to label biomolecules (proteins, peptides) for diagnostic and imaging applications.

Basic Information

Product Name	4-Hexynoic Acid
CAS No.	41143-12-8
Molecular Formula	C₆H₈O₂
Molecular Weight	112.13 g/mol
Synonyms	5-Hexynoic Acid; Hex-5-ynoic Acid; 5-Hexyn-1-oic Acid; 4-Hexyne-1-carboxylic Acid; 5-Hexyn-1-oic Acid; 1-Pentyn-4-carboxylic Acid; Butylpropiolic Acid; 4-Hexynoic acid (principal IUPAC name)
EINECS	Contact for details

Quality Control

Our 4-Hexynoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (IR, NMR), to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.