Description

3-Benzyl-6-[(Z)-Benzylidene]-2,5-Piperazinedione is a specialized diketopiperazine derivative, a class of compounds known for their significant biological and chemical relevance. This compound serves as a crucial synthetic intermediate and scaffold in advanced pharmaceutical research and fine chemical synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and CNS research.
• Peptidomimetic Scaffold: Used in medicinal chemistry to create constrained peptide analogs with enhanced metabolic stability and bioavailability.
• Chemical Biology Probe: Serves as a core structure for developing enzyme inhibitors or molecular probes to study biological pathways.
• Agrochemical Research: Intermediate in the development of new pesticides and herbicides with novel modes of action.
• Academic & Institutional R&D: Used in universities and research institutes for fundamental studies in organic synthesis and heterocyclic chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and libraries for client projects.

Basic Information

Product Name	3-Benzyl-6-[(Z)-Benzylidene]-2,5-Piperazinedione
CAS No.	40739-77-3
Molecular Formula	C19H16N2O2
Molecular Weight	304.34 g/mol
Synonyms	3-Benzyl-6-(Z)-benzylidene-2,5-piperazinedione; (Z)-3-Benzyl-6-benzylidene-2,5-piperazinedione; 3-Benzyl-6-(benzylidene)-2,5-piperazinedione; 2,5-Piperazinedione, 3-benzyl-6-[(Z)-phenylmethylene]-; (Z)-3-Benzyl-6-(phenylmethylene)piperazine-2,5-dione; 3-Benzyl-6-(Z)-phenylmethylenepiperazine-2,5-dione; Benzylidene-diketopiperazine derivative; BBP
EINECS	Contact for details

Quality Control

Our 3-Benzyl-6-[(Z)-Benzylidene]-2,5-Piperazinedione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment to ensure reliability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.