Description

1-Amino-4-Methylpiperazine Dihydrochloride Monohydrate is a high-purity, functionalized piperazine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, providing both a reactive amine group and a stable, crystalline dihydrochloride salt form for improved handling and storage. This compound is essential for research and production chemists in the pharmaceutical and agrochemical industries, where it is used to construct complex molecular architectures for active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system and as kinase inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its piperazine core for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold and ligand in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Complex Ligand Preparation: Employed in the creation of chelating agents and catalysts for asymmetric synthesis and metal complexation.
• Fine Chemical Production: Acts as a building block for dyes, pigments, and other specialty chemicals requiring a functionalized amine moiety.

Basic Information

Product Name	1-Amino-4-Methylpiperazine Dihydrochloride Monohydrate
CAS No.	40675-60-3
Molecular Formula	C5H13N3 · 2HCl · H2O
Molecular Weight	215.11 g/mol
Synonyms	4-Methyl-1-piperazinamine dihydrochloride monohydrate; 1-Amino-4-methylpiperazine dihydrochloride hydrate; 4-Methylpiperazin-1-amine dihydrochloride monohydrate; N-Amino-4-methylpiperazine dihydrochloride monohydrate; 1-Methyl-4-aminopiperazine dihydrochloride hydrate; 4-Methyl-1-aminopiperazine dihydrochloride monohydrate; AMPD · 2HCl · H2O
EINECS	Contact for details

Quality Control

Our 1-Amino-4-Methylpiperazine Dihydrochloride Monohydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent product degradation and clumping.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	7.0% - 9.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.