Description

(4-Carbamoyl-Piperidin-1-Yl)-Acetic Acid is a high-purity, versatile piperidine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a carboxamide and an acetic acid moiety, makes it an invaluable intermediate for constructing complex pharmacologically active molecules. This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetic Chemistry: Used to introduce constrained, heterocyclic scaffolds into peptide backbones to enhance stability and bioavailability.
• Ligand Synthesis for Drug Discovery: Employed in the construction of sophisticated chemical libraries for high-throughput screening and hit-to-lead optimization.
• Linker Molecule in Bioconjugation: Its bifunctional nature allows it to act as a spacer or linker in the synthesis of antibody-drug conjugates (ADCs) and other bioconjugates.
• Agrochemical Research: Serves as a precursor in the synthesis of new crop protection agents and herbicides.
• Material Science: Potential monomer or cross-linking agent for creating specialized polymers with unique properties.

Basic Information

Product Name	(4-Carbamoyl-Piperidin-1-Yl)-Acetic Acid
CAS No.	40479-21-8
Molecular Formula	C8H14N2O3
Molecular Weight	186.21 g/mol
Synonyms	1-(Carboxymethyl)-4-carbamoylpiperidine; 4-Carbamoyl-1-piperidineacetic Acid; 1-Piperidineacetic Acid, 4-carbamoyl-; (4-Carbamoyl-1-piperidinyl)acetic Acid; 4-(Aminocarbonyl)-1-piperidineacetic Acid; NSC 405124; 40479-21-8 (CAS); 4-Piperidinecarboxamide, 1-(carboxymethyl)-
EINECS	Contact for details

Quality Control

Our (4-Carbamoyl-Piperidin-1-Yl)-Acetic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.