Description

4-Hydroxysphinganine (C17 Base) is a key sphingoid base, a fundamental structural component of sphingolipids, which are essential biomolecules in cellular membranes. This compound is crucial for biochemical research and the synthesis of complex sphingolipids, enabling studies into cell signaling, apoptosis, and membrane biology. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers focused on lipidomics, drug discovery, and the production of high-value biochemical standards.

Application

• Biochemical Research Standard: Serves as a critical reference standard in lipidomics and sphingolipid metabolism studies.
• Pharmaceutical Intermediate: Used in the synthesis of novel therapeutic agents targeting sphingolipid-related pathways.
• Cell Biology Studies: Essential for investigating cell membrane structure, function, and signaling mechanisms.
• Enzyme Substrate: Acts as a substrate for enzymes like serine palmitoyltransferase in metabolic pathway analysis.
• Fine Chemical Synthesis: A building block for the custom synthesis of complex, labeled, or modified sphingolipids.
• Diagnostic Development: Potential use in developing assays for metabolic disorders related to sphingolipidosis.

Basic Information

Product Name	4-Hydroxysphinganine (C17 Base)
CAS No.	40289-37-0
Molecular Formula	C17H37NO3
Molecular Weight	303.49 g/mol
Synonyms	D-erythro-4-Hydroxysphinganine; (2S,3R,4R)-2-Amino-1,3,4-heptadecanetriol; C17-Phytosphingosine; 4-Hydroxy-D-erythro-sphinganine; Phytosphingosine (C17 base); TMS; Long-chain base
EINECS	Contact for details

Quality Control

Our 4-Hydroxysphinganine (C17 Base) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.