Description

6-Morpholin-4-Ylpyrazine-2-Carboxylic Acid is a high-purity heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its core value lies in its bifunctional structure, featuring both a morpholine-substituted pyrazine ring and a carboxylic acid group, enabling its use as a versatile intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand Synthesis: Serves as a precursor for creating complex chelating ligands used in catalysis and material science.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, dyes, and advanced materials.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new chemical spaces in drug discovery programs.

Basic Information

Product Name	6-Morpholin-4-Ylpyrazine-2-Carboxylic Acid
CAS No.	40262-73-5
Molecular Formula	C9H11N3O3
Molecular Weight	209.20 g/mol
Synonyms	6-(Morpholin-4-yl)pyrazine-2-carboxylic acid; 2-Pyrazinecarboxylic acid, 6-(4-morpholinyl)-; 6-Morpholinopyrazine-2-carboxylic acid; 4-(6-Carboxypyrazin-2-yl)morpholine; Morpholine, 4-(6-carboxy-2-pyrazinyl)-; 40262-73-5; 6-(4-Morpholinyl)-2-pyrazinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Morpholin-4-Ylpyrazine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.