Description

Per-o-(Trimethylsilyl)-β-D-Glucofuranurono-6,3-Lactone is a key protected carbohydrate derivative, specifically a fully trimethylsilylated derivative of D-glucuronic acid lactone. This compound is a crucial advanced synthetic intermediate for the preparation of complex oligosaccharides, glycoconjugates, and other bioactive molecules. It is primarily utilized by pharmaceutical research and development teams, as well as by fine chemical manufacturers specializing in custom synthesis and building blocks for drug discovery.

Application

• Glycosylation Reagent: A critical building block in the synthesis of complex oligosaccharides and glycoconjugates.
• Pharmaceutical Intermediate: Used in the research and development of novel therapeutic agents, including antiviral and anticancer drugs.
• Carbohydrate Chemistry Research: Serves as a protected precursor for studying glycosylation mechanisms and developing new synthetic methodologies.
• Fine Chemical Synthesis: Employed in the custom synthesis of specialized organic compounds for advanced material science and chemical biology.
• Bioconjugate Preparation: Used to create carbohydrate-protein or carbohydrate-small molecule conjugates for diagnostic and therapeutic applications.

Basic Information

Product Name	Per-o-(Trimethylsilyl)-β-D-Glucofuranurono-6,3-Lactone
CAS No.	40245-82-7
Molecular Formula	C15H32O6Si4
Molecular Weight	440.78 g/mol
Synonyms	1,2,5,6-Tetra-O-trimethylsilyl-β-D-glucofuranurono-6,3-lactone; β-D-Glucofuranurono-6,3-lactone, 1,2,5,6-tetrakis-O-(trimethylsilyl)-; Per-O-trimethylsilyl-D-glucurono-6,3-lactone; TMS-protected D-glucurono-γ-lactone; Fully silylated D-glucuronic acid lactone; 40245-82-7; Tetra-O-TMS-D-glucurono-γ-lactone
EINECS	Contact for details

Quality Control

Our Per-o-(Trimethylsilyl)-β-D-Glucofuranurono-6,3-Lactone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and fine chemical synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.