Description

3-Amino-6-(Chloromethyl)Pyrazinecarbonitrile is a versatile and high-value heterocyclic building block with significant synthetic utility. This compound is prized for its bifunctional reactivity, featuring both an amino group and a chloromethyl substituent on a pyrazine-carbonitrile core, enabling diverse chemical transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers.
• Chemical Biology Probes: Useful for constructing molecular probes to study biological processes and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	3-Amino-6-(Chloromethyl)Pyrazinecarbonitrile
CAS No.	40127-91-1
Molecular Formula	C6H5ClN4
Molecular Weight	168.58 g/mol
Synonyms	6-(Chloromethyl)-3-aminopyrazine-2-carbonitrile; 3-Amino-6-chloromethylpyrazine-2-carbonitrile; 2-Pyrazinecarbonitrile, 3-amino-6-(chloromethyl)-; 3-Amino-6-(chloromethyl)-2-pyrazinecarbonitrile; 40127-91-1; 6-(Chloromethyl)-3-aminopyrazinecarbonitrile
EINECS	Contact for details

Quality Control

Every batch of 3-Amino-6-(Chloromethyl)Pyrazinecarbonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.