Description

A-Sulfophenylacetyl Chloride is a key sulfonated aromatic acid chloride intermediate used in the synthesis of advanced chemical compounds. Its primary value lies in introducing both a reactive acyl chloride group and a sulfonic acid moiety, enabling the creation of water-soluble or surface-active derivatives. This compound is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop products with enhanced solubility or specific ionic characteristics.

Application

• Pharmaceutical Intermediates: Crucial for synthesizing active pharmaceutical ingredients (APIs) and prodrugs that require sulfonate groups for improved bioavailability or targeting.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the sulfophenyl group can influence solubility and systemic activity.
• Dye and Pigment Manufacturing: Serves as a building block for creating water-soluble dyes, reactive dyes, and colorants with specific ionic properties.
• Polymer Modification: Employed to introduce sulfonate functionalities into polymers, enhancing properties like hydrophilicity, ion-exchange capacity, or anti-static behavior.
• Surfactant and Detergent Chemistry: Acts as a precursor for anionic surfactants and emulsifiers used in industrial and household cleaning formulations.
• Research and Development: A valuable reagent in organic synthesis labs for constructing complex molecules with specific sulfonic acid attachments.

Basic Information

Product Name	A-Sulfophenylacetyl Chloride
CAS No.	40125-73-3
Molecular Formula	C8H7ClO4S
Molecular Weight	234.66 g/mol
Synonyms	2-(4-Sulfophenyl)acetyl Chloride; (4-Sulfophenyl)acetic Acid Chloride; p-Sulfophenylacetyl Chloride; 4-Sulfophenylacetic Acid Chloride; 2-(4-Sulfophenyl)ethanoyl Chloride; NSC 401101; α-(p-Sulfophenyl)acetyl Chloride
EINECS	Contact for details

Quality Control

Our A-Sulfophenylacetyl Chloride is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including assay, impurity profiling, and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, physical characteristics, and test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from moisture, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in polar aprotic solvents (e.g., DMF, DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.