Description

1-Dimethylaminonaphthalene-5-Sulfonyl-D-Tryptophan Ethyl Ester is a specialized, high-purity chemical derivative of tryptophan, functionalized with a dansyl (5-dimethylaminonaphthalene-1-sulfonyl) fluorophore group. This compound is valued for its role as a key intermediate and analytical reagent in advanced biochemical and pharmaceutical research. It is primarily sought by professionals in the life sciences sector for applications requiring sensitive fluorescence detection and labeling. The product is supplied with a commitment to stringent quality control to ensure batch-to-batch consistency for critical research and development work.

Application

• Fluorescent Labeling Reagent: Used for the derivatization and sensitive detection of amino acids, peptides, and proteins in HPLC and capillary electrophoresis.
• Biochemical Research Intermediate: Serves as a crucial building block in the synthesis of more complex fluorescent probes and enzyme substrates.
• Pharmaceutical Development: Employed in the research and analytical testing of novel drug candidates, particularly those targeting neurological pathways.
• Proteomics and Metabolomics: Acts as a tagging agent for the quantitative analysis of low-abundance biomolecules in complex biological samples.
• Diagnostic Assay Development: Utilized in creating fluorescent conjugates for immunoassays and other clinical diagnostic tools.

Basic Information

Product Name	1-Dimethylaminonaphthalene-5-Sulfonyl-D-Tryptophan Ethyl Ester
CAS No.	4982-85-8
Molecular Formula	C25H27N3O4S
Molecular Weight	465.56 g/mol
Synonyms	Dansyl-D-Tryptophan Ethyl Ester; Dns-D-Trp-OEt; 5-(Dimethylamino)naphthalene-1-sulfonyl-D-tryptophan ethyl ester; Nα-Dansyl-D-tryptophan ethyl ester; 1-Dimethylaminonaphthalene-5-sulphonyl-D-tryptophan ethyl ester; DANSYL-D-TRYPTOPHAN ETHYL ESTER; Ethyl N-[(1S)-1-[(1H-indol-3-yl)methyl]-2-ethoxy-2-oxoethyl]-5-(dimethylamino)naphthalene-1-sulfonamide
EINECS	Contact for details

Quality Control

Our 1-Dimethylaminonaphthalene-5-Sulfonyl-D-Tryptophan Ethyl Ester is manufactured under controlled conditions to ensure high purity and performance for research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substance data is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.