Description

(3As)-3,3Aβ,4,5,6,6Aβ,9Aα,9Bα-Octahydro-6β,9-Dimethyl-3-Methyleneazuleno[4,5-B]Furan-2,7-Dione is a complex sesquiterpene lactone derivative with a fused azulene-furan structure, offering a unique chemical scaffold for advanced synthesis. This compound matters as a high-value chemical intermediate and research building block for developing novel active molecules. It is needed by R&D chemists and process development teams in the pharmaceutical and fine chemical industries for drug discovery and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of complex natural product analogs and potential therapeutic agents.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fine Chemical Synthesis: Acts as a specialized building block for creating high-value, structurally intricate fragrance and flavor compounds.
• Academic & Industrial R&D: Employed in methodological studies exploring new cyclization and functionalization reactions of polycyclic systems.
• Material Science Precursor: Investigated for the development of organic semiconductors or advanced polymers with specific optical properties.

Basic Information

Product Name	(3As)-3,3Aβ,4,5,6,6Aβ,9Aα,9Bα-Octahydro-6β,9-Dimethyl-3-Methyleneazuleno[4,5-B]Furan-2,7-Dione
CAS No.	4668-72-8
Molecular Formula	C15H18O3
Molecular Weight	246.30 g/mol
Synonyms	6β,9-Dimethyl-3-methylenepentaleno[1,6a-b]furan-2,7-dione; 3-Methyleneazuleno[4,5-b]furan-2,7-dione derivative; Alantolactone isomer; Isoalantolactone related compound; Helenin analog; Sesquiterpene lactone, octahydro-dimethyl-methylene-; (3aS,6S,6aR,9aS,9bR)-3,3a,4,5,6,6a,9a,9b-Octahydro-6,9-dimethyl-3-methylenenaphtho[1,2-c]furan-1(3H)-one
EINECS	Contact for details

Quality Control

Our production of (3As)-3,3Aβ,4,5,6,6Aβ,9Aα,9Bα-Octahydro-6β,9-Dimethyl-3-Methyleneazuleno[4,5-B]Furan-2,7-Dione adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure specification compliance and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.