Description

3-β-Hydroxy-12-Oxo-5-β-Cholanoicacid is a high-purity bile acid derivative with significant importance in advanced pharmaceutical research and synthesis. This compound serves as a critical intermediate in the development of novel therapeutic agents and diagnostic tools targeting metabolic and liver-related pathways. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality building blocks for complex organic synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the synthesis of steroidal drugs and novel therapeutic agents.
• Biochemical Research: Used in metabolic pathway studies, enzyme inhibition assays, and as a reference standard in analytical laboratories.
• Diagnostic Reagent Development: Employed in the formulation of calibrators and controls for clinical diagnostic tests related to liver function and bile acid metabolism.
• Fine Chemical Synthesis: Serves as a chiral building block for the production of complex organic molecules in custom synthesis projects.
• Reference Standard: Provides a high-purity compound for quality control and method validation in pharmaceutical analysis (HPLC, LC-MS).

Basic Information

Product Name	3-β-Hydroxy-12-Oxo-5-β-Cholanoicacid
CAS No.	4560-58-1
Molecular Formula	C24H38O4
Molecular Weight	390.56 g/mol
Synonyms	3β-Hydroxy-12-oxo-5β-cholan-24-oic Acid; 12-Oxolithocholic Acid; 12-Ketolithocholic Acid; 3β-Hydroxy-12-oxocholanoic Acid; 5β-Cholan-24-oic acid, 3β-hydroxy-12-oxo-; 12-Oxo-3β-hydroxy-5β-cholanoic acid; NSC 113986
EINECS	Contact for details

Quality Control

Our 3-β-Hydroxy-12-Oxo-5-β-Cholanoicacid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) documenting all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.