Description

Ligustilide is a principal bioactive phthalide compound found in traditional Chinese herbs such as *Angelica sinensis* (Danggui) and *Ligusticum chuanxiong*. This compound matters for its significant role in research and development within the pharmaceutical and nutraceutical sectors, particularly for its studied biological activities. It is needed by manufacturers and R&D laboratories in the pharmaceutical, cosmetic, and herbal supplement industries for applications ranging from active pharmaceutical ingredient (API) development to functional product formulation.

Application

• Pharmaceutical intermediate for the research and development of new therapeutic agents.
• Key reference standard and active ingredient in traditional Chinese medicine (TCM) and herbal supplement formulations.
• Biochemical research tool for studying mechanisms related to inflammation, neuroprotection, and cardiovascular health.
• Functional ingredient in cosmeceutical products targeting skin health and anti-aging.
• Starting material for the semi-synthesis of related phthalide derivatives.
• Analytical standard for quality control and authentication of herbal extracts in the nutraceutical industry.

Basic Information

Product Name	Ligustilide
CAS No.	4431-01-0
Molecular Formula	C12H14O2
Molecular Weight	190.24 g/mol
Synonyms	3-Butylidene-4,5-dihydrophthalide; 3-Butylidene-1(3H)-isobenzofuranone; Senkyunolide; (Z)-Ligustilide; (3Z)-3-Butylidene-1(3H)-isobenzofuranone; Phthalide, 3-butylidene-4,5-dihydro-; Danggui lactone; Chuanxiong lactone
EINECS	Contact for details

Quality Control

Our Ligustilide is produced under strict quality management systems to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substance determination. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere for long-term stability. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	Pale yellow to yellow oily liquid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.