Description

Niflumic Acid CAS NO 4394-00-7 is a non-steroidal anti-inflammatory drug (NSAID) belonging to the fenamate class, recognized for its potent cyclooxygenase (COX) inhibitory activity. This compound is a critical pharmaceutical intermediate and active ingredient valued for its anti-inflammatory and analgesic properties. It is primarily required by manufacturers in the pharmaceutical industry for the development and production of analgesic and anti-inflammatory medications, as well as by research institutions for biochemical studies.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active component in prescription and over-the-counter anti-inflammatory and analgesic drug formulations.
• Research Chemical: Utilized in biochemical and pharmacological research to study COX enzyme inhibition, inflammation pathways, and pain mechanisms.
• Veterinary Medicine: Incorporated into treatments for managing pain and inflammation in animals.
• Reference Standard: Serves as a high-purity standard in analytical laboratories for quality control and method development in pharmaceutical analysis.
• Intermediate Synthesis: Used as a key building block in the synthesis of more complex pharmaceutical compounds and derivatives.

Basic Information

Product Name	Niflumic Acid
CAS No.	4394-00-7
Molecular Formula	C13H9F3N2O2
Molecular Weight	282.22 g/mol
Synonyms	2-{[3-(Trifluoromethyl)phenyl]amino}nicotinic acid; N-(3-Trifluoromethylphenyl)anthranilic acid; Fenazox; UP 83; R 368C; JDL 37; Acidum niflumicum; Nifluril
EINECS	224-522-5

Quality Control

Our Niflumic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by FT-IR and NMR, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) detailing all test results are provided to guarantee traceability, consistency, and compliance with relevant standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.