Description

Cholesteryl Phosphate CAS NO 4358-16-1 is a high-purity, synthetic phospholipid derivative of cholesterol, serving as a critical building block for advanced biomimetic materials. Its unique amphiphilic structure enables the formation of stable, functionalized liposomes and lipid bilayers, which are essential for targeted drug delivery and membrane research. This compound is primarily utilized by pharmaceutical R&D teams, formulation scientists, and academic researchers in life sciences for developing next-generation therapeutic systems and studying cellular membrane dynamics.

Application

• Liposome and Lipid Nanoparticle (LNP) Formulation: A key phospholipid component for constructing stable, stealth, or targeted drug delivery vehicles for mRNA, siRNA, and small molecule therapeutics.
• Biomimetic Membrane Models: Used in the creation of supported lipid bilayers (SLBs) and giant unilamellar vesicles (GUVs) for studying membrane protein interactions, permeability, and cell signaling.
• Cosmetic and Dermal Delivery Systems: Incorporated into niosomes and transfersomes to enhance the skin penetration and stability of active cosmetic ingredients.
• Diagnostic Reagent Preparation: Serves as a functional coating or anchor point for biosensors and diagnostic assays requiring a stable lipid interface.
• Biomaterials and Surface Modification: Employed to modify material surfaces with biocompatible lipid layers for medical implants and tissue engineering scaffolds.
• Biochemical Research: A vital reagent for investigating cholesterol metabolism, lipid raft formation, and the role of phospholipids in cellular processes.

Basic Information

Product Name	Cholesteryl Phosphate
CAS No.	4358-16-1
Molecular Formula	C27H47O4P
Molecular Weight	466.63 g/mol
Synonyms	Cholesterol 3-Phosphate; 3β-Cholest-5-en-3-ol 3-Phosphate; Cholesteryl Dihydrogen Phosphate; Cholesterol Phosphate; 5-Cholesten-3β-ol 3-Phosphate; Phosphoric Acid Cholesteryl Ester; Cholest-5-en-3β-yl Dihydrogen Phosphate
EINECS	224-441-7

Quality Control

Our Cholesteryl Phosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in chloroform, DMSO; sparingly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.