Description

3-Chloropivaloyl Chloride is a versatile and highly reactive organochlorine compound that serves as a crucial acylating agent and building block in advanced organic synthesis. Its value lies in its ability to introduce the 3-chloropivaloyl moiety, a key structural feature for modifying the physical and biological properties of target molecules. This intermediate is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of prodrugs and compounds with enhanced metabolic stability.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the chloropivaloyl group can improve efficacy and environmental profile.
• Polymer Chemistry: Acts as a monomer or modifier in the production of specialty polymers, resins, and coatings to impart specific chemical resistance or functional properties.
• Organic Synthesis Reagent: Employed as a reactive acyl chloride in Friedel-Crafts acylation, esterification, and amidation reactions to construct complex molecular architectures.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of specialized dyes and pigments, contributing to color fastness and performance characteristics.
• Liquid Crystal and Electronic Materials: Used in the synthesis of precursors for liquid crystals and other electronic chemicals that require precise molecular design.

Basic Information

Item	Details
Product Name	3-Chloropivaloyl Chloride
CAS No.	4300-97-4
Molecular Formula	C5H8Cl2O
Molecular Weight	155.02 g/mol
Synonyms	3-Chloro-2,2-dimethylpropanoyl Chloride; Pivaloyl Chloride, 3-Chloro-; 3-Chloro-2,2-dimethylpropionyl Chloride; NSC 408124; 3-Chloropivalic Acid Chloride; 3-Chloro-2,2-dimethylpropanoic Acid Chloride; α-Chloropivaloyl Chloride; 3-Chloro-2,2-dimethylpropanoyl Chloride
EINECS	224-337-5

Quality Control

Our 3-Chloropivaloyl Chloride is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including GC and HPLC, to monitor critical parameters such as assay and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.