Description

Clofenamic Acid is a non-steroidal anti-inflammatory drug (NSAID) belonging to the fenamate class, known for its potent cyclooxygenase (COX) inhibitory activity. This compound serves as a critical pharmacologically active ingredient and a valuable reference standard in pharmaceutical research and development. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in drug discovery, metabolic studies, and analytical method development.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel anti-inflammatory and analgesic drug candidates.
• Reference Standard: Used for quality control, method validation, and calibration in analytical laboratories (HPLC, GC-MS).
• Biochemical Research: Employed as a selective COX enzyme inhibitor to study inflammatory pathways and prostaglandin biosynthesis.
• Veterinary Medicine: Investigated for potential applications in animal health products for pain and inflammation management.
• Academic Research: A tool compound for pharmacological and pharmacokinetic studies in university and institutional labs.

Basic Information

Product Name	Clofenamic Acid
CAS No.	4295-55-0
Molecular Formula	C13H10ClNO2
Molecular Weight	247.68 g/mol
Synonyms	2-[(2,6-Dichloro-3-methylphenyl)amino]benzoic Acid; N-(2,6-Dichloro-m-tolyl)anthranilic Acid; Clofenamate; Clofenamic Acid; Meclofenamic Acid Impurity; NSC 115973; BA 72384; Fenamate Derivative
EINECS	224-307-1

Quality Control

Our Clofenamic Acid is manufactured under a cGMP-compliant quality management system, ensuring traceability and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including identity confirmation (IR, NMR), purity assay (HPLC), and impurity profiling. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with in-house specifications developed for research and pharmaceutical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.