Description

2-Vinylpyrazine is a versatile heterocyclic building block characterized by its reactive vinyl group attached to a pyrazine ring. This compound matters as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where it is used to introduce the pyrazine moiety. Industries that require fine chemical synthesis, such as pharmaceutical R&D, agrochemical manufacturing, and specialty material science, are the primary users of this high-value intermediate. Its unique structure facilitates the creation of novel compounds with targeted biological or material properties.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), especially in the development of antiviral, anticancer, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyrazine ring contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysts for organic transformations.
• Material Science Research: Employed in the development of organic semiconductors, conductive polymers, and advanced organic frameworks due to its electron-deficient aromatic system.
• Flavor and Fragrance Industry: Acts as a starting material for synthesizing specific pyrazine-based aroma compounds, though typically in high-purity grades.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in heterocyclic and medicinal chemistry for creating novel compound libraries.

Basic Information

Product Name	2-Vinylpyrazine
CAS No.	4177-16-6
Molecular Formula	C6H6N2
Molecular Weight	106.12 g/mol
Synonyms	Vinylpyrazine; 2-Ethenylpyrazine; Pyrazine, 2-ethenyl-; 2-Vinyl-1,4-diazine; 2-Vinylpyrazine; 2-Pyrazinyl ethylene; 4177-16-6 (CAS)
EINECS	224-058-6

Quality Control

Our 2-Vinylpyrazine is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. For customers with specific requirements, we can align our quality protocols with cGMP, ISO, or other relevant industry standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile and light-sensitive nature, containers must be kept tightly sealed when not in use to prevent evaporation and photodegradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%
Refractive Index	To be provided on COA
Boiling Point	~ 78-80°C / 15 mmHg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.