Description

4-Phenyl-1-(p-Tolylsulphonyl)Piperazine is a specialized piperazine derivative featuring a phenyl and a p-tolylsulfonyl substituent, serving as a crucial synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing novel active compounds and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its piperazine core for bioactivity.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Academic & Institutional R&D: Fundamental research reagent in universities and research institutes for methodological studies and novel reaction development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	4-Phenyl-1-(p-Tolylsulphonyl)Piperazine
CAS No.	4004-96-0
Molecular Formula	C17H20N2O2S
Molecular Weight	316.42 g/mol
Synonyms	1-(4-Methylphenyl)sulfonyl-4-phenylpiperazine; 4-Phenyl-1-(4-tolylsulfonyl)piperazine; 4-Phenyl-1-tosylpiperazine; N-(p-Tolylsulfonyl)-N'-phenylpiperazine; 1-Tosyl-4-phenylpiperazine; 4004-96-0; 4-Phenyl-1-(p-toluenesulfonyl)piperazine
EINECS	Contact for details

Quality Control

Our 4-Phenyl-1-(p-Tolylsulphonyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.