Description

2-Hydroxy-3-Methylvaleric Acid is a chiral hydroxy acid with significant utility as a versatile building block in organic synthesis. Its value lies in its ability to introduce both hydroxyl and carboxylic acid functionalities, enabling the construction of complex molecules for advanced applications. This compound is particularly relevant for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking high-purity intermediates for research and production.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting metabolic and neurological pathways.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where specific stereochemistry is required for bioactivity.
• Flavor and Fragrance Industry: Serves as a precursor for lactones and esters that contribute to complex flavor profiles and aromatic compounds.
• Biochemical Research: Employed as a standard or reagent in enzymatic studies and metabolic pathway analysis due to its structural similarity to natural metabolites.
• Polymer Modification: Acts as a monomer or co-monomer for producing specialty polyesters with tailored properties like biodegradability or specific hydrophilicity.
• Asymmetric Catalysis: Utilized as a ligand or a chiral auxiliary in asymmetric synthesis to induce enantioselectivity in chemical reactions.

Basic Information

Item	Detail
Product Name	2-Hydroxy-3-Methylvaleric Acid
CAS No.	488-15-3
Molecular Formula	C6H12O3
Molecular Weight	132.16 g/mol
Synonyms	3-Methyl-2-hydroxyvaleric Acid; (±)-2-Hydroxy-3-methylpentanoic Acid; 2-Hydroxy-3-methylpentanoic Acid; DL-2-Hydroxy-3-methylvaleric Acid; 3-Methyl-2-hydroxypentanoic Acid; α-Hydroxy-β-methylvaleric Acid; 488-15-3; 2-Hydroxy-3-methylpentanoate
EINECS	207-673-6

Quality Control

Our 2-Hydroxy-3-Methylvaleric Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including assay, enantiomeric purity (where applicable), and impurity profiling by HPLC, GC, and NMR to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	88°C - 92°C
Loss on Drying	≤ 1.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Optical Purity (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.